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Gene-specific Copy Number Variation Probe-PPP2R2B

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Catalog: CNVFP-PPP2R2B-16422
Classification: Copy Number Variation
Description: Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PPP2R2B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application: PPP2R2B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PPP2R2B genes. This product achieves the purpose of detection by hybridizing with the PPP2R2B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Category: Copy Number Variation
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name Protein Phosphatase 2 Regulatory Subunit Bbeta
Gene Summary [Provided by RefSeq] The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12. [provided by RefSeq, Jul 2016]
Gene Symbol PPP2R2B
Location 5q32
Chromosome Chromosome5
Coordinates This gene maps to 145969067-146461033 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 OR CNVFP-PPP2R2B-16422-OR 573nm 548nm
2 RE CNVFP-PPP2R2B-16422-RE 599nm 580nm
3 GO CNVFP-PPP2R2B-16422-GO 551nm 525nm
4 GR CNVFP-PPP2R2B-16422-GR 515nm 491nm
5 AQ CNVFP-PPP2R2B-16422-AQ 467nm 418nm

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