Gene-specific Copy Number Variation Probe-PPP1R15B
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| Catalog: |
CNVFP-PPP1R15B-16092 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PPP1R15B). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PPP1R15B Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PPP1R15B genes. This product achieves the purpose of detection by hybridizing with the PPP1R15B gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Protein Phosphatase 1 Regulatory Subunit 15B |
| Gene Summary [Provided by RefSeq] |
This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with microcephaly, short stature, and impaired glucose metabolism. [provided by RefSeq, Feb 2016] |
| Gene Symbol |
PPP1R15B |
| Location |
1q32.1 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 204372491-204380944 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PPP1R15B-16092-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PPP1R15B-16092-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PPP1R15B-16092-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PPP1R15B-16092-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PPP1R15B-16092-AQ |
467nm |
418nm |
|
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