Gene-specific Copy Number Variation Probe-PPM1A
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| Catalog: |
CNVFP-PPM1A-16119 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PPM1A). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PPM1A Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PPM1A genes. This product achieves the purpose of detection by hybridizing with the PPM1A gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Protein Phosphatase, Mg2+/Mn2+ Dependent 1A |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
PPM1A |
| Location |
14q23.1 |
| Chromosome |
Chromosome14 |
| Coordinates |
This gene maps to 60712469-60765805 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PPM1A-16119-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PPM1A-16119-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PPM1A-16119-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PPM1A-16119-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PPM1A-16119-AQ |
467nm |
418nm |
|
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