Gene-specific Copy Number Variation Probe-PLN
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Catalog: |
CNVFP-PLN-15986 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PLN). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PLN Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PLN genes. This product achieves the purpose of detection by hybridizing with the PLN gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Phospholamban |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy. [provided by RefSeq, Apr 2016] |
Gene Symbol |
PLN |
Location |
6q22.31 |
Chromosome |
Chromosome6 |
Coordinates |
This gene maps to 118869441-118881587 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PLN-15986-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PLN-15986-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PLN-15986-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PLN-15986-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PLN-15986-AQ |
467nm |
418nm |
|
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