Gene-specific Copy Number Variation Probe-PLCE1
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Catalog: |
CNVFP-PLCE1-16051 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PLCE1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PLCE1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PLCE1 genes. This product achieves the purpose of detection by hybridizing with the PLCE1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Phospholipase C Epsilon 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] |
Gene Symbol |
PLCE1 |
Location |
10q23.33 |
Chromosome |
Chromosome10 |
Coordinates |
This gene maps to 95753745-96088148 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PLCE1-16051-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PLCE1-16051-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PLCE1-16051-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PLCE1-16051-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PLCE1-16051-AQ |
467nm |
418nm |
|
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