Gene-specific Copy Number Variation Probe-PFKFB4
Add to Cart
Catalog: |
CNVFP-PFKFB4-15613 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PFKFB4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PFKFB4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PFKFB4 genes. This product achieves the purpose of detection by hybridizing with the PFKFB4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is one of four bifunctional kinase/phosphatases that regulate the concentration of the glycolytic byproduct fructose-2,6-bisphosphate (F2,6BP). The encoded protein is highly expressed in cancer cells and is induced by hypoxia. This protein is essential to the survival of cancer cells under conditions of hypoxia, because it increases the amount of F2,6BP and ATP at a time when the cell cannot produce much of them. This finding suggests that this protein may be a good target for disruption in cancer cells, hopefully imperiling their survival. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
Gene Symbol |
PFKFB4 |
Location |
3p21.31 |
Chromosome |
Chromosome3 |
Coordinates |
This gene maps to 48555116-48594227 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PFKFB4-15613-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PFKFB4-15613-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PFKFB4-15613-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PFKFB4-15613-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PFKFB4-15613-AQ |
467nm |
418nm |
|
Other Products