Gene-specific Copy Number Variation Probe-PFKFB3
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| Catalog: |
CNVFP-PFKFB3-15616 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PFKFB3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PFKFB3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PFKFB3 genes. This product achieves the purpose of detection by hybridizing with the PFKFB3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016] |
| Gene Symbol |
PFKFB3 |
| Location |
10p15.1 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 6186842-6277507 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PFKFB3-15616-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PFKFB3-15616-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PFKFB3-15616-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PFKFB3-15616-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PFKFB3-15616-AQ |
467nm |
418nm |
|
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