Gene-specific Copy Number Variation Probe-PDZD3
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Catalog: |
CNVFP-PDZD3-15516 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PDZD3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PDZD3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PDZD3 genes. This product achieves the purpose of detection by hybridizing with the PDZD3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
PDZ Domain Containing 3 |
Gene Summary [Provided by RefSeq] |
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008] |
Gene Symbol |
PDZD3 |
Location |
11q23.3 |
Chromosome |
Chromosome11 |
Coordinates |
This gene maps to 119056165-119060932 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-PDZD3-15516-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PDZD3-15516-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PDZD3-15516-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PDZD3-15516-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PDZD3-15516-AQ |
467nm |
418nm |
|
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