Gene-specific Copy Number Variation Probe-PDP1
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| Catalog: |
CNVFP-PDP1-15693 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PDP1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PDP1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PDP1 genes. This product achieves the purpose of detection by hybridizing with the PDP1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Pyruvate Dehyrogenase Phosphatase Catalytic Subunit 1 |
| Gene Summary [Provided by RefSeq] |
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009] |
| Gene Symbol |
PDP1 |
| Location |
8q22.1 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 94929082-94938296 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PDP1-15693-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PDP1-15693-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PDP1-15693-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PDP1-15693-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PDP1-15693-AQ |
467nm |
418nm |
|
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