Gene-specific Copy Number Variation Probe-PDHA1
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| Catalog: |
CNVFP-PDHA1-15376 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PDHA1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PDHA1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PDHA1 genes. This product achieves the purpose of detection by hybridizing with the PDHA1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Pyruvate Dehydrogenase E1 Alpha 1 Subunit |
| Gene Summary [Provided by RefSeq] |
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
| Gene Symbol |
PDHA1 |
| Location |
Xp22.12 |
| Chromosome |
ChromosomeX |
| Coordinates |
This gene maps to 19362010-19379825 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PDHA1-15376-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PDHA1-15376-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PDHA1-15376-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PDHA1-15376-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PDHA1-15376-AQ |
467nm |
418nm |
|
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