Gene-specific Copy Number Variation Probe-PDGFRB
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Catalog: |
CNVFP-PDGFRB-15377 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PDGFRB). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PDGFRB Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PDGFRB genes. This product achieves the purpose of detection by hybridizing with the PDGFRB gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Platelet Derived Growth Factor Receptor Beta |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017] |
Gene Symbol |
PDGFRB |
Location |
5q32 |
Chromosome |
Chromosome5 |
Coordinates |
This gene maps to 149493401-149535422 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-PDGFRB-15377-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PDGFRB-15377-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PDGFRB-15377-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PDGFRB-15377-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PDGFRB-15377-AQ |
467nm |
418nm |
|
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