Gene-specific Copy Number Variation Probe-PDF
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| Catalog: |
CNVFP-PDF-15382 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PDF). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PDF Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PDF genes. This product achieves the purpose of detection by hybridizing with the PDF gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Peptide Deformylase, Mitochondrial |
| Gene Summary [Provided by RefSeq] |
Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq, Nov 2008] |
| Gene Symbol |
PDF |
| Location |
16q22.1 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 69362523-69364498 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PDF-15382-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PDF-15382-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PDF-15382-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PDF-15382-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PDF-15382-AQ |
467nm |
418nm |
|
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