Gene-specific Copy Number Variation Probe-PCSK9
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Catalog: |
CNVFP-PCSK9-15427 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PCSK9). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PCSK9 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PCSK9 genes. This product achieves the purpose of detection by hybridizing with the PCSK9 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Proprotein Convertase Subtilisin/kexin Type 9 |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
Gene Symbol |
PCSK9 |
Location |
1p32.3 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 55505148-55530526 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-PCSK9-15427-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PCSK9-15427-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PCSK9-15427-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PCSK9-15427-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PCSK9-15427-AQ |
467nm |
418nm |
|
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