Gene-specific Copy Number Variation Probe-PCSK5
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| Catalog: |
CNVFP-PCSK5-15430 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PCSK5). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PCSK5 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PCSK5 genes. This product achieves the purpose of detection by hybridizing with the PCSK5 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Proprotein Convertase Subtilisin/kexin Type 5 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B). [provided by RefSeq, May 2014] |
| Gene Symbol |
PCSK5 |
| Location |
9q21.13 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 78505559-78977255 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PCSK5-15430-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PCSK5-15430-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PCSK5-15430-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PCSK5-15430-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PCSK5-15430-AQ |
467nm |
418nm |
|
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