Gene-specific Copy Number Variation Probe-PCSK2
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| Catalog: |
CNVFP-PCSK2-15432 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PCSK2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PCSK2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PCSK2 genes. This product achieves the purpose of detection by hybridizing with the PCSK2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Proprotein Convertase Subtilisin/kexin Type 2 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The protein undergoes an initial autocatalytic processing event and interacts with a neuroendocrine secretory protein in the ER, exits the ER and sorts to secretory granules, where it is cleaved and catalytically activated during intracellular transport. The encoded protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2014] |
| Gene Symbol |
PCSK2 |
| Location |
20p12.1 |
| Chromosome |
Chromosome20 |
| Coordinates |
This gene maps to 17206751-17465222 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PCSK2-15432-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PCSK2-15432-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PCSK2-15432-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PCSK2-15432-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PCSK2-15432-AQ |
467nm |
418nm |
|
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