Gene-specific Copy Number Variation Probe-PCA3
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| Catalog: |
CNVFP-PCA3-15247 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PCA3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PCA3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PCA3 genes. This product achieves the purpose of detection by hybridizing with the PCA3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Prostate Cancer Associated 3 (non-protein Coding) |
| Gene Summary [Provided by RefSeq] |
This gene produces a spliced, long non-coding RNA that is highly overexpressed in most types of prostate cancer cells and is used as a specific biomarker for this type of cancer. This gene is embedded in an intronic region of the prune2 gene on the opposite DNA strand. The transcript regulates prune2 levels through formation of a double-stranded RNA that undergoes adenosine deaminase acting on RNA-dependent adenosine-to-inosine RNA editing. In prostate cancer derived cells, overexpression of PCA induced downregulation of prune2, leading to decreased cell proliferation. Conversely, silencing in prostate cancer cells resulted in increased proliferation. Regulation of this gene appears to be sensitive to androgen-receptor activation, a molecular signature of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017] |
| Gene Symbol |
PCA3 |
| Location |
9q21.2 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 79379353-79402465 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PCA3-15247-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PCA3-15247-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PCA3-15247-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PCA3-15247-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PCA3-15247-AQ |
467nm |
418nm |
|
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