Gene-specific Copy Number Variation Probe-PAWR
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| Catalog: |
CNVFP-PAWR-15305 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PAWR). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
PAWR Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PAWR genes. This product achieves the purpose of detection by hybridizing with the PAWR gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Pro-apoptotic WT1 Regulator |
| Gene Summary [Provided by RefSeq] |
This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017] |
| Gene Symbol |
PAWR |
| Location |
12q21.2 |
| Chromosome |
Chromosome12 |
| Coordinates |
This gene maps to 79985744-80084790 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-PAWR-15305-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-PAWR-15305-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-PAWR-15305-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-PAWR-15305-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-PAWR-15305-AQ |
467nm |
418nm |
|
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