Gene-specific Copy Number Variation Probe-PAPPA
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Catalog: |
CNVFP-PAPPA-15315 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PAPPA). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PAPPA Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PAPPA genes. This product achieves the purpose of detection by hybridizing with the PAPPA gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Pappalysin 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017] |
Gene Symbol |
PAPPA |
Location |
9q33.1 |
Chromosome |
Chromosome9 |
Coordinates |
This gene maps to 118916070-119164600 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PAPPA-15315-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PAPPA-15315-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PAPPA-15315-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PAPPA-15315-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PAPPA-15315-AQ |
467nm |
418nm |
|
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