Gene-specific Copy Number Variation Probe-PABPC4
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Catalog: |
CNVFP-PABPC4-15046 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (PABPC4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
PABPC4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to PABPC4 genes. This product achieves the purpose of detection by hybridizing with the PABPC4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Poly(A) Binding Protein Cytoplasmic 4 |
Gene Summary [Provided by RefSeq] |
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
Gene Symbol |
PABPC4 |
Location |
1p34.3 |
Chromosome |
Chromosome1 |
Coordinates |
This gene maps to 40026484-40042521 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-PABPC4-15046-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-PABPC4-15046-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-PABPC4-15046-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-PABPC4-15046-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-PABPC4-15046-AQ |
467nm |
418nm |
|
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