Gene-specific Copy Number Variation Probe-ORC1
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| Catalog: |
CNVFP-ORC1-15157 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (ORC1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
ORC1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to ORC1 genes. This product achieves the purpose of detection by hybridizing with the ORC1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Origin Recognition Complex Subunit 1 |
| Gene Summary [Provided by RefSeq] |
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| Gene Symbol |
ORC1 |
| Location |
1p32.3 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 52838500-52870143 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-ORC1-15157-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-ORC1-15157-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-ORC1-15157-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-ORC1-15157-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-ORC1-15157-AQ |
467nm |
418nm |
|
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