Gene-specific Copy Number Variation Probe-OPTN
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Catalog: |
CNVFP-OPTN-14877 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (OPTN). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
OPTN Gene-specific copy number variation probes are mainly used to detect the copy number variation related to OPTN genes. This product achieves the purpose of detection by hybridizing with the OPTN gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Optineurin |
Gene Summary [Provided by RefSeq] |
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
Gene Symbol |
OPTN |
Location |
10p13 |
Chromosome |
Chromosome10 |
Coordinates |
This gene maps to 13142081-13180276 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-OPTN-14877-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-OPTN-14877-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-OPTN-14877-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-OPTN-14877-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-OPTN-14877-AQ |
467nm |
418nm |
|
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