Gene-specific Copy Number Variation Probe-NUDT1
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Catalog: |
CNVFP-NUDT1-14662 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NUDT1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
NUDT1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NUDT1 genes. This product achieves the purpose of detection by hybridizing with the NUDT1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Nudix Hydrolase 1 |
Gene Summary [Provided by RefSeq] |
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008] |
Gene Symbol |
NUDT1 |
Location |
7p22.3 |
Chromosome |
Chromosome7 |
Coordinates |
This gene maps to 2281856-2290780 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-NUDT1-14662-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-NUDT1-14662-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-NUDT1-14662-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-NUDT1-14662-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-NUDT1-14662-AQ |
467nm |
418nm |
|
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