Gene-specific Copy Number Variation Probe-NRG3
Add to Cart
| Catalog: |
CNVFP-NRG3-14411 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NRG3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
NRG3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NRG3 genes. This product achieves the purpose of detection by hybridizing with the NRG3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Neuregulin 3 |
| Gene Summary [Provided by RefSeq] |
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009] |
| Gene Symbol |
NRG3 |
| Location |
10q23.1 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 83635069-84746935 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-NRG3-14411-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-NRG3-14411-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-NRG3-14411-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-NRG3-14411-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-NRG3-14411-AQ |
467nm |
418nm |
|
Other Products
