Gene-specific Copy Number Variation Probe-NR3C1
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Catalog: |
CNVFP-NR3C1-14434 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NR3C1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
NR3C1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NR3C1 genes. This product achieves the purpose of detection by hybridizing with the NR3C1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Nuclear Receptor Subfamily 3 Group C Member 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011] |
Gene Symbol |
NR3C1 |
Location |
5q31.3 |
Chromosome |
Chromosome5 |
Coordinates |
This gene maps to 142657495-142815077 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-NR3C1-14434-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-NR3C1-14434-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-NR3C1-14434-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-NR3C1-14434-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-NR3C1-14434-AQ |
467nm |
418nm |
|
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