Gene-specific Copy Number Variation Probe-NR1H2
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Catalog: |
CNVFP-NR1H2-14463 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NR1H2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
NR1H2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NR1H2 genes. This product achieves the purpose of detection by hybridizing with the NR1H2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Nuclear Receptor Subfamily 1 Group H Member 2 |
Gene Summary [Provided by RefSeq] |
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010] |
Gene Symbol |
NR1H2 |
Location |
19q13.33 |
Chromosome |
Chromosome19 |
Coordinates |
This gene maps to 50879684-50886267 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-NR1H2-14463-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-NR1H2-14463-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-NR1H2-14463-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-NR1H2-14463-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-NR1H2-14463-AQ |
467nm |
418nm |
|
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