Gene-specific Copy Number Variation Probe-NOTCH1
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| Catalog: |
CNVFP-NOTCH1-14168 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NOTCH1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
NOTCH1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NOTCH1 genes. This product achieves the purpose of detection by hybridizing with the NOTCH1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Notch 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016] |
| Gene Symbol |
NOTCH1 |
| Location |
9q34.3 |
| Chromosome |
Chromosome9 |
| Coordinates |
This gene maps to 139388895-139440238 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-NOTCH1-14168-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-NOTCH1-14168-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-NOTCH1-14168-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-NOTCH1-14168-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-NOTCH1-14168-AQ |
467nm |
418nm |
|
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