Gene-specific Copy Number Variation Probe-NFKB1
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| Catalog: |
CNVFP-NFKB1-14038 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NFKB1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
NFKB1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NFKB1 genes. This product achieves the purpose of detection by hybridizing with the NFKB1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Nuclear Factor Kappa B Subunit 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Feb 2016] |
| Gene Symbol |
NFKB1 |
| Location |
4q24 |
| Chromosome |
Chromosome4 |
| Coordinates |
This gene maps to 103422485-103538459 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-NFKB1-14038-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-NFKB1-14038-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-NFKB1-14038-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-NFKB1-14038-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-NFKB1-14038-AQ |
467nm |
418nm |
|
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