Gene-specific Copy Number Variation Probe-NEDD4L
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Catalog: |
CNVFP-NEDD4L-14111 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NEDD4L). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
NEDD4L Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NEDD4L genes. This product achieves the purpose of detection by hybridizing with the NEDD4L gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Neural Precursor Cell Expressed, Developmentally Down-regulated 4-like, E3 Ubiquitin Protein Ligase |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
Gene Symbol |
NEDD4L |
Location |
18q21.31 |
Chromosome |
Chromosome18 |
Coordinates |
This gene maps to 55711609-56068772 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-NEDD4L-14111-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-NEDD4L-14111-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-NEDD4L-14111-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-NEDD4L-14111-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-NEDD4L-14111-AQ |
467nm |
418nm |
|
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