Gene-specific Copy Number Variation Probe-NCSTN
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| Catalog: |
CNVFP-NCSTN-13811 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NCSTN). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
NCSTN Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NCSTN genes. This product achieves the purpose of detection by hybridizing with the NCSTN gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Nicastrin |
| Gene Summary [Provided by RefSeq] |
This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Feb 2014] |
| Gene Symbol |
NCSTN |
| Location |
1q23.2 |
| Chromosome |
Chromosome1 |
| Coordinates |
This gene maps to 160313062-160328742 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-NCSTN-13811-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-NCSTN-13811-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-NCSTN-13811-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-NCSTN-13811-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-NCSTN-13811-AQ |
467nm |
418nm |
|
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