Gene-specific Copy Number Variation Probe-NCF4
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| Catalog: |
CNVFP-NCF4-13852 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (NCF4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
NCF4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to NCF4 genes. This product achieves the purpose of detection by hybridizing with the NCF4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Neutrophil Cytosolic Factor 4 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
NCF4 |
| Location |
22q12.3 |
| Chromosome |
Chromosome22 |
| Coordinates |
This gene maps to 37257029-37274059 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-NCF4-13852-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-NCF4-13852-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-NCF4-13852-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-NCF4-13852-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-NCF4-13852-AQ |
467nm |
418nm |
|
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