Gene-specific Copy Number Variation Probe-MUS81

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Catalog:	CNVFP-MUS81-13621
Classification:	Copy Number Variation
Description:	Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MUS81). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services.
Application:	MUS81 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MUS81 genes. This product achieves the purpose of detection by hybridizing with the MUS81 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	7-10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Name	MUS81 Structure-specific Endonuclease Subunit
Gene Summary [Provided by RefSeq]	This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017]
Gene Symbol	MUS81
Location	11q13.1
Chromosome	Chromosome11
Coordinates	This gene maps to 65627871-65633914 in GRCh37 coordinates.
Species	Human

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