Gene-specific Copy Number Variation Probe-MSR1
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| Catalog: |
CNVFP-MSR1-13452 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MSR1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MSR1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MSR1 genes. This product achieves the purpose of detection by hybridizing with the MSR1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Macrophage Scavenger Receptor 1 |
| Gene Summary [Provided by RefSeq] |
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
MSR1 |
| Location |
8p22 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 15965386-16050300 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MSR1-13452-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MSR1-13452-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MSR1-13452-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MSR1-13452-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MSR1-13452-AQ |
467nm |
418nm |
|
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