Gene-specific Copy Number Variation Probe-MSH6
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Catalog: |
CNVFP-MSH6-13477 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MSH6). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
MSH6 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MSH6 genes. This product achieves the purpose of detection by hybridizing with the MSH6 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
MutS Homolog 6 |
Gene Summary [Provided by RefSeq] |
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] |
Gene Symbol |
MSH6 |
Location |
2p16.3 |
Chromosome |
Chromosome2 |
Coordinates |
This gene maps to 48010220-48034092 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-MSH6-13477-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-MSH6-13477-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-MSH6-13477-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-MSH6-13477-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-MSH6-13477-AQ |
467nm |
418nm |
|
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