Gene-specific Copy Number Variation Probe-MRVI1
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| Catalog: |
CNVFP-MRVI1-13487 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MRVI1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MRVI1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MRVI1 genes. This product achieves the purpose of detection by hybridizing with the MRVI1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Murine Retrovirus Integration Site 1 Homolog |
| Gene Summary [Provided by RefSeq] |
This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used. [provided by RefSeq, May 2011] |
| Gene Symbol |
MRVI1 |
| Location |
11p15.4 |
| Chromosome |
Chromosome11 |
| Coordinates |
This gene maps to 10594637-10715535 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MRVI1-13487-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MRVI1-13487-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MRVI1-13487-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MRVI1-13487-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MRVI1-13487-AQ |
467nm |
418nm |
|
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