Gene-specific Copy Number Variation Probe-MRPS12
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Catalog: |
CNVFP-MRPS12-13534 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MRPS12). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
MRPS12 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MRPS12 genes. This product achieves the purpose of detection by hybridizing with the MRPS12 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Mitochondrial Ribosomal Protein S12 |
Gene Summary [Provided by RefSeq] |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein. [provided by RefSeq, Jul 2008] |
Gene Symbol |
MRPS12 |
Location |
19q13.2 |
Chromosome |
Chromosome19 |
Coordinates |
This gene maps to 39421347-39423659 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-MRPS12-13534-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-MRPS12-13534-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-MRPS12-13534-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-MRPS12-13534-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-MRPS12-13534-AQ |
467nm |
418nm |
|
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