Gene-specific Copy Number Variation Probe-MMP2
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| Catalog: |
CNVFP-MMP2-13350 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MMP2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MMP2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MMP2 genes. This product achieves the purpose of detection by hybridizing with the MMP2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Matrix Metallopeptidase 2 |
| Gene Summary [Provided by RefSeq] |
This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] |
| Gene Symbol |
MMP2 |
| Location |
16q12.2 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 55513080-55540586 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MMP2-13350-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MMP2-13350-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MMP2-13350-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MMP2-13350-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MMP2-13350-AQ |
467nm |
418nm |
|
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