Gene-specific Copy Number Variation Probe-MLKL
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| Catalog: |
CNVFP-MLKL-13380 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MLKL). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MLKL Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MLKL genes. This product achieves the purpose of detection by hybridizing with the MLKL gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Mixed Lineage Kinase Domain Like Pseudokinase |
| Gene Summary [Provided by RefSeq] |
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015] |
| Gene Symbol |
MLKL |
| Location |
16q23.1 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 74705752-74734789 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MLKL-13380-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MLKL-13380-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MLKL-13380-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MLKL-13380-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MLKL-13380-AQ |
467nm |
418nm |
|
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