Gene-specific Copy Number Variation Probe-MLH1
Add to Cart
| Catalog: |
CNVFP-MLH1-13384 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MLH1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MLH1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MLH1 genes. This product achieves the purpose of detection by hybridizing with the MLH1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
MutL Homolog 1 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). [provided by RefSeq, Aug 2017] |
| Gene Symbol |
MLH1 |
| Location |
3p22.2 |
| Chromosome |
Chromosome3 |
| Coordinates |
This gene maps to 37034840-37092337 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MLH1-13384-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MLH1-13384-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MLH1-13384-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MLH1-13384-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MLH1-13384-AQ |
467nm |
418nm |
|
Other Products
