Gene-specific Copy Number Variation Probe-MKNK2
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| Catalog: |
CNVFP-MKNK2-13396 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MKNK2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MKNK2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MKNK2 genes. This product achieves the purpose of detection by hybridizing with the MKNK2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
MAP Kinase Interacting Serine/threonine Kinase 2 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011] |
| Gene Symbol |
MKNK2 |
| Location |
19p13.3 |
| Chromosome |
Chromosome19 |
| Coordinates |
This gene maps to 2037469-2051243 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MKNK2-13396-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MKNK2-13396-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MKNK2-13396-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MKNK2-13396-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MKNK2-13396-AQ |
467nm |
418nm |
|
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