Gene-specific Copy Number Variation Probe-MGMT
Add to Cart
| Catalog: |
CNVFP-MGMT-11190 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MGMT). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MGMT Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MGMT genes. This product achieves the purpose of detection by hybridizing with the MGMT gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
O-6-methylguanine-DNA Methyltransferase |
| Gene Summary [Provided by RefSeq] |
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015] |
| Gene Symbol |
MGMT |
| Location |
10q26.3 |
| Chromosome |
Chromosome10 |
| Coordinates |
This gene maps to 131265453-131565783 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MGMT-11190-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MGMT-11190-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MGMT-11190-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MGMT-11190-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MGMT-11190-AQ |
467nm |
418nm |
|
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