Gene-specific Copy Number Variation Probe-MECP2
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Catalog: |
CNVFP-MECP2-10981 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MECP2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
MECP2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MECP2 genes. This product achieves the purpose of detection by hybridizing with the MECP2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Methyl-CpG Binding Protein 2 |
Gene Summary [Provided by RefSeq] |
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of cognitive disability in females. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015] |
Gene Symbol |
MECP2 |
Location |
Xq28 |
Chromosome |
ChromosomeX |
Coordinates |
This gene maps to 153287263-153363188 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-MECP2-10981-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-MECP2-10981-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-MECP2-10981-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-MECP2-10981-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-MECP2-10981-AQ |
467nm |
418nm |
|
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