Gene-specific Copy Number Variation Probe-MCM4
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| Catalog: |
CNVFP-MCM4-11037 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MCM4). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MCM4 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MCM4 genes. This product achieves the purpose of detection by hybridizing with the MCM4 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Minichromosome Maintenance Complex Component 4 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
MCM4 |
| Location |
8q11.21 |
| Chromosome |
Chromosome8 |
| Coordinates |
This gene maps to 48872762-48890719 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MCM4-11037-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MCM4-11037-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MCM4-11037-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MCM4-11037-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MCM4-11037-AQ |
467nm |
418nm |
|
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