Gene-specific Copy Number Variation Probe-MC1R
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| Catalog: |
CNVFP-MC1R-11059 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MC1R). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MC1R Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MC1R genes. This product achieves the purpose of detection by hybridizing with the MC1R gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Melanocortin 1 Receptor |
| Gene Summary [Provided by RefSeq] |
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
MC1R |
| Location |
16q24.3 |
| Chromosome |
Chromosome16 |
| Coordinates |
This gene maps to 89984286-89987385 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MC1R-11059-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MC1R-11059-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MC1R-11059-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MC1R-11059-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MC1R-11059-AQ |
467nm |
418nm |
|
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