Gene-specific Copy Number Variation Probe-MBD5
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| Catalog: |
CNVFP-MBD5-11076 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MBD5). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MBD5 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MBD5 genes. This product achieves the purpose of detection by hybridizing with the MBD5 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Methyl-CpG Binding Domain Protein 5 |
| Gene Summary [Provided by RefSeq] |
This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause an autosomal dominant type of cognitive disability. The encoded protein interacts with the polycomb repressive complex PR-DUB which catalyzes the deubiquitination of a lysine residue of histone 2A. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq, Jul 2017] |
| Gene Symbol |
MBD5 |
| Location |
2q23.1 |
| Chromosome |
Chromosome2 |
| Coordinates |
This gene maps to 148778579-149271044 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MBD5-11076-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MBD5-11076-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MBD5-11076-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MBD5-11076-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MBD5-11076-AQ |
467nm |
418nm |
|
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