Gene-specific Copy Number Variation Probe-MASP1
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Catalog: |
CNVFP-MASP1-10997 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MASP1). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
MASP1 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MASP1 genes. This product achieves the purpose of detection by hybridizing with the MASP1 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Mannan Binding Lectin Serine Peptidase 1 |
Gene Summary [Provided by RefSeq] |
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] |
Gene Symbol |
MASP1 |
Location |
3q27.3 |
Chromosome |
Chromosome3 |
Coordinates |
This gene maps to 186933872-187009810 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-MASP1-10997-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-MASP1-10997-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-MASP1-10997-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-MASP1-10997-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-MASP1-10997-AQ |
467nm |
418nm |
|
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