Gene-specific Copy Number Variation Probe-MAPK14
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Catalog: |
CNVFP-MAPK14-10841 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MAPK14). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
MAPK14 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MAPK14 genes. This product achieves the purpose of detection by hybridizing with the MAPK14 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Mitogen-activated Protein Kinase 14 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Gene Symbol |
MAPK14 |
Location |
6p21.31 |
Chromosome |
Chromosome6 |
Coordinates |
This gene maps to 35995453-36079013 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
OR
|
CNVFP-MAPK14-10841-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-MAPK14-10841-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-MAPK14-10841-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-MAPK14-10841-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-MAPK14-10841-AQ |
467nm |
418nm |
|
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