Gene-specific Copy Number Variation Probe-MAP3K5
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| Catalog: |
CNVFP-MAP3K5-10863 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MAP3K5). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MAP3K5 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MAP3K5 genes. This product achieves the purpose of detection by hybridizing with the MAP3K5 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Mitogen-activated Protein Kinase Kinase Kinase 5 |
| Gene Summary [Provided by RefSeq] |
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
MAP3K5 |
| Location |
6q23.3 |
| Chromosome |
Chromosome6 |
| Coordinates |
This gene maps to 136878186-137113656 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MAP3K5-10863-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MAP3K5-10863-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MAP3K5-10863-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MAP3K5-10863-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MAP3K5-10863-AQ |
467nm |
418nm |
|
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