Gene-specific Copy Number Variation Probe-MAP3K3
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| Catalog: |
CNVFP-MAP3K3-10864 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MAP3K3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MAP3K3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MAP3K3 genes. This product achieves the purpose of detection by hybridizing with the MAP3K3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Mitogen-activated Protein Kinase Kinase Kinase 3 |
| Gene Summary [Provided by RefSeq] |
This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
MAP3K3 |
| Location |
17q23.3 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 61699800-61773670 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MAP3K3-10864-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MAP3K3-10864-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MAP3K3-10864-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MAP3K3-10864-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MAP3K3-10864-AQ |
467nm |
418nm |
|
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