Gene-specific Copy Number Variation Probe-MAP2K3
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| Catalog: |
CNVFP-MAP2K3-10877 |
| Classification: |
Copy Number Variation |
| Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MAP2K3). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
| Application: |
MAP2K3 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MAP2K3 genes. This product achieves the purpose of detection by hybridizing with the MAP2K3 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
| Category: |
Copy Number Variation |
| Probe Kits Volume (µL): |
40 μL |
| Quantity: |
20 Tests |
| Hybridization Solution (µL): |
200 μL |
| Turnaround Time: |
7-10 Business Days |
| Shipping Time: |
1-2 Day Expedited Shipping |
| Storage Conditions: |
Store at -20℃ and avoid light; |
| Shipping Conditions: |
-20℃ |
Gene Details
| Gene Name |
Mitogen-activated Protein Kinase Kinase 3 |
| Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol |
MAP2K3 |
| Location |
17p11.2 |
| Chromosome |
Chromosome17 |
| Coordinates |
This gene maps to 21187967-21218551 in GRCh37 coordinates. |
| Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
| Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
| 1 |
OR
|
CNVFP-MAP2K3-10877-OR |
573nm |
548nm |
|
| 2 |
RE
|
CNVFP-MAP2K3-10877-RE |
599nm |
580nm |
|
| 3 |
GO
|
CNVFP-MAP2K3-10877-GO |
551nm |
525nm |
|
| 4 |
GR
|
CNVFP-MAP2K3-10877-GR |
515nm |
491nm |
|
| 5 |
AQ
|
CNVFP-MAP2K3-10877-AQ |
467nm |
418nm |
|
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