Gene-specific Copy Number Variation Probe-MAP2K2
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Catalog: |
CNVFP-MAP2K2-10879 |
Classification: |
Copy Number Variation |
Description: |
Our Gene-specific Copy Number Variation Probes usually target the flanks of the target gene (MAP2K2). The product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We provide CNV FISH Probes with a variety of dye color combinations to meet various challenges. Probe products not only provide some classic color combinations but also provide customized probe services. |
Application: |
MAP2K2 Gene-specific copy number variation probes are mainly used to detect the copy number variation related to MAP2K2 genes. This product achieves the purpose of detection by hybridizing with the MAP2K2 gene. Due to this design method, our probe products can detect the amplification and deletion of target genes on chromosomes through FISH. |
Category: |
Copy Number Variation |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name |
Mitogen-activated Protein Kinase Kinase 2 |
Gene Summary [Provided by RefSeq] |
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008] |
Gene Symbol |
MAP2K2 |
Location |
19p13.3 |
Chromosome |
Chromosome19 |
Coordinates |
This gene maps to 4090319-4124126 in GRCh37 coordinates. |
Species |
Human |
Dye Colors:
OR
RE
GO
GR
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
OR
|
CNVFP-MAP2K2-10879-OR |
573nm |
548nm |
|
2 |
RE
|
CNVFP-MAP2K2-10879-RE |
599nm |
580nm |
|
3 |
GO
|
CNVFP-MAP2K2-10879-GO |
551nm |
525nm |
|
4 |
GR
|
CNVFP-MAP2K2-10879-GR |
515nm |
491nm |
|
5 |
AQ
|
CNVFP-MAP2K2-10879-AQ |
467nm |
418nm |
|
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